Saccharomyces cerevisiaeGenAge entry for GCN5 (Saccharomyces cerevisiae)

Gene information (ID: 295)

Symbol
GCN5
Aliases
AAS104; ADA4; SWI9
Name
Histone acetyltransferase
Organism
Saccharomyces cerevisiae (AnAge)

Potential relevance to longevity and/or ageing

Observations
Deletion suppressed extension of replicative lifespan.
Lifespan Effect
Decrease
Genetic Manipulation
Deletion
Longevity Category
Necessary for fitness
Primary reference
    Observations
    Strongly reduced chronological lifespan
    Lifespan Effect
    Decrease
    Genetic Manipulation
    Deletion
    Longevity Category
    Necessary for fitness
    Primary reference
      Observations
      Mean chronological lifespan strongly decreased in the a strain
      Lifespan Effect
      Decrease
      Genetic Manipulation
      Deletion
      Longevity Category
      Necessary for fitness
      Primary reference
        Observations
        Mean chronological lifespan decreased in the a strain by more than 50%
        % change in avg or median lifespan
        Mean chronological lifespan is more than 50% lower.
        Lifespan Effect
        Decrease
        Genetic Manipulation
        Deletion
        Longevity Category
        Necessary for fitness
        Primary reference

          In other databases

          CellAge
          • A homolog of this gene for Homo sapiens is present as BAZ1A
          CellAge gene expression
          • A homolog of this gene for Homo sapiens is present as BAZ1B
          • A homolog of this gene for Homo sapiens is present as BAZ1A

          Homologs in other organisms

          Caenorhabditis elegans
          athp-2
          Caenorhabditis elegans
          baz-2
          Caenorhabditis elegans
          pcaf-1
          Caenorhabditis elegans
          nurf-1
          Danio rerio
          baz2ba
          Danio rerio
          im:6907928
          Danio rerio
          bptf
          Danio rerio
          baz2a
          Danio rerio
          kat2a
          Danio rerio
          kat2b
          Danio rerio
          BAZ1A
          Danio rerio
          baz1b
          Danio rerio
          BAZ2B (1 of many)
          Danio rerio
          cecr2
          Drosophila melanogaster
          E(bx)
          Drosophila melanogaster
          Acf1
          Drosophila melanogaster
          dikar
          Drosophila melanogaster
          Gcn5
          Drosophila melanogaster
          tou
          Homo sapiens
          BAZ1A
          Homo sapiens
          BAZ1B
          Homo sapiens
          CECR2
          Homo sapiens
          BAZ2A
          Homo sapiens
          BAZ2B
          Homo sapiens
          KAT2A
          Homo sapiens
          KAT2B
          Homo sapiens
          BPTF
          Mus musculus
          Baz2b
          Mus musculus
          Cecr2
          Mus musculus
          Bptf
          Mus musculus
          Baz2a
          Mus musculus
          Baz1a
          Mus musculus
          Baz1b
          Mus musculus
          Kat2b
          Mus musculus
          Kat2a
          Rattus norvegicus
          Kat2b
          Rattus norvegicus
          Baz2a
          Rattus norvegicus
          Kat2a
          Rattus norvegicus
          Baz2b
          Rattus norvegicus
          Cecr2
          Rattus norvegicus
          Baz1a
          Rattus norvegicus
          Bptf
          Rattus norvegicus
          Baz1b
          Schizosaccharomyces pombe
          gcn5

          External links

          Saccharomyces Genome Database
          Search
          Ensembl
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          Entrez Gene
          View on Entrez Gene database (853167)
          Homologues
          Search HomoloGene
          UniProt
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          Internet
          Search Google or Search Google Scholar