Caenorhabditis elegansGenAge entry for lbp-8 (Caenorhabditis elegans)

Gene information (ID: 1882)

Symbol
lbp-8
Name
Lipid Binding Protein
Organism
Caenorhabditis elegans (AnAge)

Potential relevance to longevity and/or ageing

Observations
RNA interference (or mutation/deletion) of lbp-8 suppresses the lifespan extension in the lipl-4 transgenic model and does not affect the WT lifespan. Contrastly, constitutive transgenic expression of lbp-8 results in a 30% increase in mean lifespan compared to WT and improved maintenance of physical activity with age.
% change in max lifespan
Maximum lifespan is aproximately 22% higher.
% change in avg or median lifespan
Mean lifespan is 30% higher.
Lifespan Effect
Increase
Genetic Manipulation
Overexpression
Longevity Category
Pro-Longevity
Primary reference

    In other databases

    GenAge model organism genes
    • A homolog of this gene for Drosophila melanogaster is present as fabp
    GenAge microarray genes
    • A homolog of this gene for Homo sapiens is present as FABP5
    • A homolog of this gene for Homo sapiens is present as RBP1
    GenDR gene expression
    • A homolog of this gene for Mus musculus is present as Fabp5
    • A homolog of this gene for Mus musculus is present as Rbp7
    CellAge
    • A homolog of this gene for Homo sapiens is present as RBP1
    • A homolog of this gene for Homo sapiens is present as RBP2
    CellAge gene expression
    • A homolog of this gene for Homo sapiens is present as FABP5
    • A homolog of this gene for Homo sapiens is present as RBP1

    Homologs in other organisms

    Danio rerio
    rbp5
    Danio rerio
    fabp3
    Danio rerio
    rbp7b
    Danio rerio
    fabp7a
    Danio rerio
    CABZ01088982.1
    Danio rerio
    rbp7a
    Danio rerio
    RBP1
    Danio rerio
    rbp1
    Danio rerio
    crabp2a
    Danio rerio
    crabp1a
    Danio rerio
    fabp7b
    Danio rerio
    rbp2a
    Danio rerio
    crabp2b
    Danio rerio
    fabp11b
    Danio rerio
    fabp11a
    Danio rerio
    rbp2b
    Danio rerio
    crabp1b
    Drosophila melanogaster
    fabp
    Homo sapiens
    FABP9
    Homo sapiens
    RBP5
    Homo sapiens
    RBP7
    Homo sapiens
    FABP12
    Homo sapiens
    FABP7
    Homo sapiens
    PMP2
    Homo sapiens
    RBP1
    Homo sapiens
    RBP2
    Homo sapiens
    FABP5
    Homo sapiens
    FABP3
    Homo sapiens
    CRABP1
    Homo sapiens
    CRABP2
    Homo sapiens
    FABP4
    Mus musculus
    Fabp4
    Mus musculus
    Gm37389
    Mus musculus
    Fabp7
    Mus musculus
    Crabp1
    Mus musculus
    Rbp7
    Mus musculus
    Rbp2
    Mus musculus
    Fabp9
    Mus musculus
    Fabp12
    Mus musculus
    Rbp1
    Mus musculus
    Fabp3
    Mus musculus
    Pmp2
    Mus musculus
    Crabp2
    Mus musculus
    Fabp5
    Rattus norvegicus
    Fabp12
    Rattus norvegicus
    Rbp7
    Rattus norvegicus
    Pmp2
    Rattus norvegicus
    Fabp3
    Rattus norvegicus
    Rbp1
    Rattus norvegicus
    Rbp2
    Rattus norvegicus
    Crabp2
    Rattus norvegicus
    Crabp1
    Rattus norvegicus
    Fabp9
    Rattus norvegicus
    Fabp7
    Rattus norvegicus
    Fabp4
    Rattus norvegicus
    Crabp2
    Rattus norvegicus
    Fabp5

    External links

    WormBase
    Search
    Ensembl
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    Entrez Gene
    View on Entrez Gene database (188761)
    Homologues
    Search HomoloGene
    UniProt
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    Internet
    Search Google or Search Google Scholar