Saccharomyces cerevisiaeGenAge entry for TDA5 (Saccharomyces cerevisiae)

Gene information (ID: 1434)

Symbol
TDA5
Name
Topoisomerase I Damage Affected
Organism
Saccharomyces cerevisiae (AnAge)

Potential relevance to longevity and/or ageing

Observations
Replicative lifespan decreased by 30% in the alpha strain
% change in avg or median lifespan
Replicative lifespan is 30% lower.
Lifespan Effect
Decrease
Genetic Manipulation
Deletion
Longevity Category
Necessary for fitness
Primary reference

    In other databases

    CellAge gene expression
    • A homolog of this gene for Homo sapiens is present as DHRS3

    Homologs in other organisms

    Caenorhabditis elegans
    dhs-4
    Caenorhabditis elegans
    dhs-3
    Caenorhabditis elegans
    dhs-29
    Caenorhabditis elegans
    dhs-19
    Danio rerio
    dhrs3a
    Danio rerio
    sdr16c5b
    Danio rerio
    rdh10b
    Danio rerio
    sdr16c5a
    Danio rerio
    dhrs3b
    Danio rerio
    rdh20
    Danio rerio
    rdh10a
    Danio rerio
    563950
    Drosophila melanogaster
    CG2254
    Drosophila melanogaster
    CG15629
    Drosophila melanogaster
    CG14946
    Drosophila melanogaster
    CG17121
    Drosophila melanogaster
    CG13833
    Drosophila melanogaster
    CG9265
    Homo sapiens
    HSD17B13
    Homo sapiens
    SDR16C5
    Homo sapiens
    HSD17B11
    Homo sapiens
    RDH10
    Homo sapiens
    DHRS3
    Mus musculus
    Sdr16c5
    Mus musculus
    Rdh10
    Mus musculus
    Dhrs3
    Mus musculus
    Hsd17b11
    Mus musculus
    Hsd17b13
    Mus musculus
    Sdr16c6
    Rattus norvegicus
    Sdr16c5
    Rattus norvegicus
    Hsd17b11
    Rattus norvegicus
    Hsd17b13
    Rattus norvegicus
    Dhrs3
    Rattus norvegicus
    Sdr16c6
    Rattus norvegicus
    Rdh10
    Schizosaccharomyces pombe
    SPBC16H5.14c

    External links

    Saccharomyces Genome Database
    Search
    Ensembl
    Search
    Entrez Gene
    View on Entrez Gene database (851146)
    Homologues
    Search HomoloGene
    UniProt
    Search
    Internet
    Search Google or Search Google Scholar