Saccharomyces cerevisiaeGenAge entry for MSH2 (Saccharomyces cerevisiae)

Gene information (ID: 1371)

Symbol
MSH2
Aliases
PMS5
Name
MutS Homolog
Organism
Saccharomyces cerevisiae (AnAge)

Potential relevance to longevity and/or ageing

Observations
Mean chronological lifespan decreased in the a strain by less than 50% but more than 15%
% change in avg or median lifespan
Mean chronological lifespan is 15%-50% lower.
Lifespan Effect
Decrease
Genetic Manipulation
Deletion
Longevity Category
Necessary for fitness
Primary reference

    In other databases

    GenAge model organism genes
    • A homolog of this gene for Mus musculus is present as Msh2
    LongevityMap
    • A homolog of this gene for Homo sapiens is present as MSH2
    CellAge gene expression
    • A homolog of this gene for Homo sapiens is present as MSH2

    Homologs in other organisms

    Caenorhabditis elegans
    msh-2
    Danio rerio
    msh2
    Drosophila melanogaster
    spel1
    Homo sapiens
    MSH2
    Mus musculus
    Msh2
    Rattus norvegicus
    Msh2
    Schizosaccharomyces pombe
    msh2

    External links

    Saccharomyces Genome Database
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (854063)
    Homologues
    Search HomoloGene
    UniProt
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    Internet
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