Caenorhabditis elegansGenAge entry for hpk-1 (Caenorhabditis elegans)

Gene information (ID: 338)

Symbol
hpk-1
Name
Homeodomain interacting Protein Kinase
Organism
Caenorhabditis elegans (AnAge)
Known functions and activities
Homeodomain interacting protein kinase

Potential relevance to longevity and/or ageing

Observations
RNA interference decreased median lifespan by 37% in wild type animals and 40% in daf-2 mutants.
% change in avg or median lifespan
Median lifespan is 37% lower.
Lifespan Effect
Decrease
Genetic Manipulation
RNA interference
Longevity Category
Pro-Longevity
Primary reference

    In other databases

    GenAge model organism genes
    • A homolog of this gene for Saccharomyces cerevisiae is present as YAK1
    GenDR gene expression
    • A homolog of this gene for Mus musculus is present as Hipk2

    Homologs in other organisms

    Danio rerio
    hipk3b
    Danio rerio
    hipk1a
    Danio rerio
    HIPK1 (1 of many)
    Danio rerio
    hipk3a
    Danio rerio
    hipk2
    Drosophila melanogaster
    hipk
    Homo sapiens
    HIPK2
    Homo sapiens
    HIPK3
    Homo sapiens
    HIPK1
    Mus musculus
    Hipk1
    Mus musculus
    Hipk2
    Mus musculus
    Hipk3
    Rattus norvegicus
    Hipk1
    Rattus norvegicus
    Hipk2
    Rattus norvegicus
    Hipk3
    Saccharomyces cerevisiae
    YAK1

    External links

    WormBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (180695)
    Homologues
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    UniProt
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    Internet
    Search Google or Search Google Scholar