Caenorhabditis elegansGenAge entry for dlat-1 (Caenorhabditis elegans)

Gene information (ID: 2030)

Symbol
dlat-1
Name
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex
Organism
Caenorhabditis elegans (AnAge)

Potential relevance to longevity and/or ageing

Observations
RNA interference of F23B12.5 results in an increased lifespan.
% change in avg or median lifespan
Mean lifespan is 9.9% higher.
Lifespan Effect
Increase
Genetic Manipulation
RNA interference
Longevity Category
Anti-Longevity
Primary reference

    In other databases

    GenAge model organism genes
    • A homolog of this gene for Saccharomyces cerevisiae is present as LAT1
    GenAge microarray genes
    • A homolog of this gene for Homo sapiens is present as DLAT
    GenDR gene manipulations
    • A homolog of this gene for Saccharomyces cerevisiae is present as LAT1

    Homologs in other organisms

    Danio rerio
    dlat
    Drosophila melanogaster
    CG5261
    Homo sapiens
    DLAT
    Mus musculus
    Dlat
    Rattus norvegicus
    Dlat
    Saccharomyces cerevisiae
    LAT1
    Schizosaccharomyces pombe
    lat1

    External links

    WormBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (179945)
    Homologues
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    UniProt
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    Internet
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