- Symbol
- cdc-48.1
- Name
- Protein CDC-48.1
- Organism
- Caenorhabditis elegans (AnAge)
- Observations
- In contrast to single deletions, worms deficient for both cdc-48.1 (p97) and atx-3 have an extended lifespan, modulated through the insulin/IGF-1 signalling pathway.
- % change in avg or median lifespan
- Lifespan is up to 50% higher.
- Lifespan Effect
- Increase
- Genetic Manipulation
- Mutation
- Longevity Category
- Anti-Longevity
- Primary reference
-
- GenAge human genes
- A homolog of this gene for Homo sapiens is present as VCP
- Danio rerio
- zgc:136908
- Danio rerio
- vcp
- Drosophila melanogaster
- TER94
- Homo sapiens
- VCP
- Mus musculus
- Vcp
- Rattus norvegicus
- Vcp
- Saccharomyces cerevisiae
- CDC48
- WormBase
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (174624)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar
GenAge entry for cdc-48.1 (Caenorhabditis elegans)