- Symbol
- atg-7
- Name
- AuTophaGy (yeast Atg homolog)
- Organism
- Caenorhabditis elegans (AnAge)
- Known functions and activities
- Autophagic vesicle expansion
- Observations
- RNA interference shortened mean lifespan by 23% and maximum lifespan by 30% in a eat-2 mutant background but not in wild type animals.
- Lifespan Effect
- Not Recorded
- Genetic Manipulation
- RNA interference
- Longevity Category
- Pro-Longevity
- Primary reference
-
- Observations
- Post developmental RNAi resulted in a 10-15% maxumal lifespan extension compared to wild type. No lifespan extension by RNAi from the beginning of life.
- % change in max lifespan
- Maximum lifespan is 10-15% higher.
- Lifespan Effect
- Increase
- Genetic Manipulation
- RNA interference
- Longevity Category
- Anti-Longevity
- Primary reference
-
- GenAge model organism genes
- A homolog of this gene for Drosophila melanogaster is present as Atg7
- A homolog of this gene for Saccharomyces cerevisiae is present as ATG7
- GenDR gene manipulations
- A homolog of this gene for Saccharomyces cerevisiae is present as ATG7
- This gene is present as atg-7
- CellAge
- A homolog of this gene for Homo sapiens is present as ATG7
- Danio rerio
- atg7
- Drosophila melanogaster
- Atg7
- Homo sapiens
- ATG7
- Mus musculus
- Atg7
- Rattus norvegicus
- Atg7
- Saccharomyces cerevisiae
- ATG7
- Schizosaccharomyces pombe
- atg7
- WormBase
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (178005)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar
GenAge entry for atg-7 (Caenorhabditis elegans)