GenDR Dietary Restriction Gene Manipulation: atg-7
Gene Information (Entrez Gene ID: 178005)
- Symbol
- atg-7
- Name
- AuTophaGy (yeast Atg homolog) 7
- Organism
- Caenorhabditis elegans (AnAge)
- Entrez Gene ID
- 178005
Potential relevance to dietary restriction and ageing
- Observations
-
RNA interference against atg-7 shortens mean lifespan by 23% and maximum lifespan by 30% in a eat-2 mutant background but not in wild-type animals. Thus, atg-7 RNAi does not affect lifespan of wild-type, but cancels out the lifespan extension effect of eat-2 mutation, a genetic model of DR [2244].
- References
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In other databases
- GenAge model organism genes
- GenDR gene manipulations
- A homolog of this gene for Saccharomyces cerevisiae is present as ATG7
- CellAge
- A homolog of this gene for Homo sapiens is present as ATG7
Homologs
- Danio rerio
- atg7
- Drosophila melanogaster
- Atg7
- Homo sapiens
- ATG7
- Mus musculus
- Atg7
- Rattus norvegicus
- Atg7
- Saccharomyces cerevisiae
- ATG7
- Schizosaccharomyces pombe
- atg7
External links
- WormBase
- Search
- Ensembl
- Search
- Entrez Gene
- ID 178005
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar