Caenorhabditis elegansGenAge entry for alg-2 (Caenorhabditis elegans)

Gene information (ID: 11)

Symbol
alg-2
Name
Argonaute (plant)-Like Gene
Organism
Caenorhabditis elegans (AnAge)
Known functions and activities
Post-transcriptional gene silencing

Potential relevance to longevity and/or ageing

Observations
RNA interference decreased median lifespan by 24% in wild type animals and 50% in a daf-2 background.
% change in avg or median lifespan
Median lifespan is 24% lower.
Lifespan Effect
Decrease
Genetic Manipulation
RNA interference
Longevity Category
Pro-Longevity
Primary reference

    In other databases

    CellAge
    • A homolog of this gene for Homo sapiens is present as AGO2

    Homologs in other organisms

    Danio rerio
    ago2
    Drosophila melanogaster
    AGO1
    Homo sapiens
    AGO2
    Mus musculus
    Ago2
    Rattus norvegicus
    Ago2

    External links

    WormBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (173468)
    Homologues
    Search HomoloGene
    UniProt
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    Internet
    Search Google or Search Google Scholar