- Symbol
- TPO1
- Name
- Transporter of POlyamines
- Organism
- Saccharomyces cerevisiae (AnAge)
- Observations
- Deletion caused mean replicative lifespan decrease by 8.2% in the alpha strain and by 31.5% in the a strain
- % change in avg or median lifespan
- Replicative lifespan is 8-32% lower.
- Lifespan Effect
- Decrease
- Genetic Manipulation
- Deletion
- Longevity Category
- Necessary for fitness
- Primary reference
-
- Observations
- Overexpression caused replicative lifespan increase by 24.4% in the alpha strain and by 21.4% in the a strain
- % change in avg or median lifespan
- Replicative lifespan is 21-25% higher.
- Lifespan Effect
- Increase
- Genetic Manipulation
- Overexpression
- Longevity Category
- Pro-Longevity
- Primary reference
-
- Schizosaccharomyces pombe
- SPBC530.15c
- Saccharomyces Genome Database
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (850631)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar
GenAge entry for TPO1 (Saccharomyces cerevisiae)