- Symbol
- TOM1
- Name
- Temperature dependent Organization in Mitotic nucleus
- Organism
- Saccharomyces cerevisiae (AnAge)
- Observations
- Tom1 mutants exhibit increased replicative lifespan.
- % change in avg or median lifespan
- Mean replicative lifespan is 30% higher.
- Lifespan Effect
- Increase
- Genetic Manipulation
- Deletion
- Longevity Category
- Anti-Longevity
- Primary reference
-
- Observations
- Replicative lifespan increased by 10%-20% in the alpha and a strains
- % change in avg or median lifespan
- Replicative lifespan is 10-20% higher.
- Lifespan Effect
- Increase
- Genetic Manipulation
- Deletion
- Longevity Category
- Anti-Longevity
- Primary reference
-
- Caenorhabditis elegans
- ubr-5
- Caenorhabditis elegans
- eel-1
- Danio rerio
- ubr5
- Danio rerio
- huwe1
- Drosophila melanogaster
- hyd
- Drosophila melanogaster
- CG8184
- Homo sapiens
- HUWE1
- Homo sapiens
- UBR5
- Mus musculus
- Ubr5
- Mus musculus
- Huwe1
- Rattus norvegicus
- Huwe1
- Rattus norvegicus
- Ubr5
- Schizosaccharomyces pombe
- ptr1
- Saccharomyces Genome Database
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (852068)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar