Saccharomyces cerevisiaeGenAge entry for SSC1 (Saccharomyces cerevisiae)

Gene information (ID: 2110)

Symbol
SSC1
Name
Hsp70 family ATPase SSC1
Organism
Saccharomyces cerevisiae (AnAge)

Potential relevance to longevity and/or ageing

Observations
Loss of the chaperone SSC1 in yeast triggers the activation of a cross-organelle stress response (CORE). Mean replicative lifespan after SSC1 deletion increased by 40%. Chronological lifespan also increased by 15%.
% change in avg or median lifespan
Mean replicative lifespan is 40% higher.
Lifespan Effect
Increase
Genetic Manipulation
Deletion
Longevity Category
Anti-Longevity
Primary reference

    In other databases

    GenAge model organism genes
    • A homolog of this gene for Caenorhabditis elegans is present as hsp-6
    GenAge human genes
    • A homolog of this gene for Homo sapiens is present as HSPA9

    Homologs in other organisms

    Caenorhabditis elegans
    hsp-6
    Danio rerio
    hspa9
    Drosophila melanogaster
    Hsc70-5
    Homo sapiens
    HSPA9
    Mus musculus
    Hspa9
    Rattus norvegicus
    Hspa9

    External links

    Saccharomyces Genome Database
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (853503)
    Homologues
    Search HomoloGene
    UniProt
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    Internet
    Search Google or Search Google Scholar