GenAge entry for MCA1 (Saccharomyces cerevisiae)
Gene information (ID: 1916)
- Symbol
- MCA1
- Aliases
- YCA1
- Name
- Ca(2+)-dependent cysteine protease MCA1
- Organism
- Saccharomyces cerevisiae (AnAge)
Potential relevance to longevity and/or ageing
- Observations
- Lack of Mca1 has little effect on replicative life span in wild type yeast cells, and an accelerated aging effect in cells also lacking Ydj1. Overexpression of Mca1 extends lifespan by 46-56% in a Ydj1 dependent manner.
- % change in avg or median lifespan
- Median lifespan is 46-56% higher.
- Lifespan Effect
- Increase
- Genetic Manipulation
- Overexpression
- Longevity Category
- Pro-Longevity
- Primary reference
-
Homologs in other organisms
- Schizosaccharomyces pombe
- pca1
External links
- Saccharomyces Genome Database
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (854372)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar