- Symbol
- DIE2
- Aliases
- ALG10
- Name
- Derepression of ITR1 Expression
- Organism
- Saccharomyces cerevisiae (AnAge)
- Observations
- Deletion of die2, a target of the unfolded protein response signaling, decreases replicative lifespan.
- % change in avg or median lifespan
- Mean lifespan is 17% lower.
- Lifespan Effect
- Increase
- Genetic Manipulation
- Deletion
- Longevity Category
- Anti-Longevity
- Primary reference
-
- Observations
- Mean chronological lifespan increased in the a strain by less than 50% but more than 15%
- % change in avg or median lifespan
- Mean chronological lifespan is 15%-50% higher.
- Lifespan Effect
- Increase
- Genetic Manipulation
- Deletion
- Longevity Category
- Anti-Longevity
- Primary reference
-
- Caenorhabditis elegans
- tag-179
- Danio rerio
- alg10
- Drosophila melanogaster
- Alg10
- Homo sapiens
- ALG10
- Mus musculus
- Alg10b
- Rattus norvegicus
- Alg10b
- Schizosaccharomyces pombe
- alg10
- Saccharomyces Genome Database
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (853142)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar
GenAge entry for DIE2 (Saccharomyces cerevisiae)