Saccharomyces cerevisiaeGenAge entry for CHD1 (Saccharomyces cerevisiae)

Gene information (ID: 1360)

Symbol
CHD1
Name
Chromatin organization modifier, Helicase, and DNA-binding domains
Organism
Saccharomyces cerevisiae (AnAge)

Potential relevance to longevity and/or ageing

Observations
Deletion of CHD1 in yeast extends replicative lifespan by 14%.
% change in avg or median lifespan
Median replicative lifespan is 14% higher.
Lifespan Effect
Increase
Genetic Manipulation
Deletion
Longevity Category
Anti-Longevity
Primary reference
    Observations
    Mean chronological lifespan decreased in the a strain by less than 50% but more than 15%
    % change in avg or median lifespan
    Mean chronological lifespan is 15%-50% lower.
    Lifespan Effect
    Decrease
    Genetic Manipulation
    Deletion
    Longevity Category
    Necessary for fitness
    Primary reference

      In other databases

      GenAge model organism genes
      • A homolog of this gene for Caenorhabditis elegans is present as let-418

      Homologs in other organisms

      Caenorhabditis elegans
      let-418
      Caenorhabditis elegans
      chd-7
      Caenorhabditis elegans
      chd-3
      Caenorhabditis elegans
      chd-1
      Danio rerio
      chd1
      Danio rerio
      chd4b
      Danio rerio
      chd2
      Danio rerio
      chd7
      Danio rerio
      chd5
      Danio rerio
      chd9
      Danio rerio
      chd6
      Danio rerio
      chd8
      Danio rerio
      chd4a
      Danio rerio
      chd3
      Drosophila melanogaster
      kis
      Drosophila melanogaster
      Chd1
      Drosophila melanogaster
      Chd3
      Drosophila melanogaster
      Mi-2
      Homo sapiens
      CHD6
      Homo sapiens
      CHD8
      Homo sapiens
      CHD3
      Homo sapiens
      CHD2
      Homo sapiens
      CHD1
      Homo sapiens
      CHD4
      Homo sapiens
      CHD5
      Homo sapiens
      CHD9
      Homo sapiens
      CHD7
      Mus musculus
      Chd7
      Mus musculus
      Chd5
      Mus musculus
      Chd6
      Mus musculus
      Chd1
      Mus musculus
      Chd1
      Mus musculus
      Chd8
      Mus musculus
      Chd4
      Mus musculus
      Chd3
      Mus musculus
      Chd9
      Mus musculus
      Chd2
      Rattus norvegicus
      Chd4
      Rattus norvegicus
      Chd8
      Rattus norvegicus
      Chd9
      Rattus norvegicus
      Chd3
      Rattus norvegicus
      Chd1
      Rattus norvegicus
      Chd2
      Rattus norvegicus
      Chd5
      Rattus norvegicus
      Chd7
      Rattus norvegicus
      Chd6
      Schizosaccharomyces pombe
      hrp1

      External links

      Saccharomyces Genome Database
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      Ensembl
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      Entrez Gene
      View on Entrez Gene database (856911)
      Homologues
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      UniProt
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      Internet
      Search Google or Search Google Scholar