Saccharomyces cerevisiaeGenAge entry for CDC25 (Saccharomyces cerevisiae)

Gene information (ID: 105)

Symbol
CDC25
Aliases
CTN1
Name
Cdc25p
Organism
Saccharomyces cerevisiae (AnAge)
Known functions and activities
Cell cycle regulation

Potential relevance to longevity and/or ageing

Observations
Knockout mutants live about 50% longer than controls.
% change in avg or median lifespan
Lifespan is about 50% higher.
Lifespan Effect
Increase
Genetic Manipulation
Knockout
Longevity Category
Anti-Longevity
Primary reference

    In other databases

    GenDR gene manipulations
    • This gene is present as CDC25
    LongevityMap
    • A homolog of this gene for Homo sapiens is present as SOS1

    Homologs in other organisms

    Caenorhabditis elegans
    Y34B4A.4
    Caenorhabditis elegans
    sos-1
    Caenorhabditis elegans
    rgl-1
    Danio rerio
    rgl3a
    Danio rerio
    sos2
    Danio rerio
    799483
    Danio rerio
    rasgrf2b
    Danio rerio
    RASGRF2 (1 of many)
    Danio rerio
    ralgps1
    Danio rerio
    RASGRF1
    Danio rerio
    rapgef1a
    Danio rerio
    rapgef1b
    Danio rerio
    rgl1
    Danio rerio
    RGL3 (1 of many)
    Danio rerio
    rgl2
    Danio rerio
    ralgps2
    Danio rerio
    sos1
    Danio rerio
    FO834898.1
    Drosophila melanogaster
    Rgl
    Drosophila melanogaster
    CG5522
    Drosophila melanogaster
    C3G
    Drosophila melanogaster
    Sos
    Homo sapiens
    RGL4
    Homo sapiens
    RALGPS2
    Homo sapiens
    SOS1
    Homo sapiens
    RASGRF2
    Homo sapiens
    SOS2
    Homo sapiens
    RGL3
    Homo sapiens
    RALGPS1
    Homo sapiens
    RASGRF1
    Homo sapiens
    RGL1
    Homo sapiens
    RAPGEF1
    Homo sapiens
    RGL2
    Homo sapiens
    RALGDS
    Mus musculus
    Rasgrf2
    Mus musculus
    Rasgrf1
    Mus musculus
    Rgl1
    Mus musculus
    Rapgef1
    Mus musculus
    Ralgps2
    Mus musculus
    Rgl3
    Mus musculus
    Ralgds
    Mus musculus
    Sos2
    Mus musculus
    Rgl2
    Mus musculus
    Sos1
    Mus musculus
    Ralgps1
    Rattus norvegicus
    Ralgps1
    Rattus norvegicus
    Sos2
    Rattus norvegicus
    AABR07007642.1
    Rattus norvegicus
    Rapgef1
    Rattus norvegicus
    Ralgds
    Rattus norvegicus
    Rasgrf1
    Rattus norvegicus
    Rgl1
    Rattus norvegicus
    Ralgps2
    Rattus norvegicus
    Rgl3
    Rattus norvegicus
    Rgl2
    Rattus norvegicus
    Sos1

    External links

    Saccharomyces Genome Database
    Search
    Ensembl
    Search
    Entrez Gene
    View on Entrez Gene database (851019)
    Homologues
    Search HomoloGene
    UniProt
    Search
    Internet
    Search Google or Search Google Scholar