GenAge entry for CAN1 (Saccharomyces cerevisiae)
Gene information (ID: 2224)
- Symbol
- CAN1
- Name
- arginine permease CAN1
- Organism
- Saccharomyces cerevisiae (AnAge)
Potential relevance to longevity and/or ageing
- Observations
- Deletion of CAN1 in yeast increased mean replicative lifespan by 30%. This increase was dependent on the Gcn4 and Hac1 transcription factors and reduced mTOR signalling.
- % change in avg or median lifespan
- Mean replicative lifespan is 30% higher.
- Lifespan Effect
- Increase
- Genetic Manipulation
- Deletion
- Longevity Category
- Anti-Longevity
- Primary reference
-
Homologs in other organisms
No homologs found
External links
- Saccharomyces Genome Database
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (856646)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar