GenAge entry for CAN1 (Saccharomyces cerevisiae)
Gene information (ID: 2224)
- arginine permease CAN1
- Saccharomyces cerevisiae (AnAge)
Potential relevance to longevity and/or ageing
- Deletion of CAN1 in yeast increased mean replicative lifespan by 30%. This increase was dependent on the Gcn4 and Hac1 transcription factors and reduced mTOR signalling.
- % change in avg or median lifespan
- Mean replicative lifespan is 30% higher.
- Lifespan Effect
- Genetic Manipulation
- Longevity Category
- Primary reference
Homologs in other organisms
No homologs found