Mus musculusGenAge entry for Agtr1a (Mus musculus)

Gene information (ID: 811)

Symbol
Agtr1a
Aliases
AT1; AG2S; AT1a; AT2R1; Agtr1; AT2R1A; Agtr-1a; AI551199;
Name
Angiotensin II receptor, type 1a
Organism
Mus musculus (AnAge)

Potential relevance to longevity and/or ageing

Observations
KO mice showed a significant prolongation of average and maximal lifespan compared to wt.
% change in max lifespan
Maximum lifespan is 24% higher.
% change in avg or median lifespan
Average lifespan is 26% higher.
Lifespan Effect
Increase
Genetic Manipulation
Knockout
Longevity Category
Anti-Longevity
Primary reference

    In other databases

    GenAge human genes
    • A homolog of this gene for Homo sapiens is present as AGTR1
    LongevityMap
    • A homolog of this gene for Homo sapiens is present as AGTR1

    Homologs in other organisms

    Danio rerio
    agtr1b
    Danio rerio
    agtr1a
    Homo sapiens
    AGTR1
    Rattus norvegicus
    Agtr1a

    External links

    Mouse Genome Informatics
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (11607)
    Homologues
    Search HomoloGene
    UniProt
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    Internet
    Search Google or Search Google Scholar