Saccharomyces cerevisiaeGenAge entry for APL2 (Saccharomyces cerevisiae)

Gene information (ID: 1485)

Symbol
APL2
Name
clathrin Adaptor Protein complex Large chain
Organism
Saccharomyces cerevisiae (AnAge)

Potential relevance to longevity and/or ageing

Observations
Replicative lifespan decreased by 25% in the alpha strain
% change in avg or median lifespan
Replicative lifespan is 25% lower.
Lifespan Effect
Decrease
Genetic Manipulation
Deletion
Longevity Category
Necessary for fitness
Primary reference

    Homologs in other organisms

    Caenorhabditis elegans
    apb-1
    Danio rerio
    ap4b1
    Danio rerio
    ap2b1
    Danio rerio
    ap1b1
    Drosophila melanogaster
    AP-1-2beta
    Homo sapiens
    AP4B1
    Homo sapiens
    AP1B1
    Homo sapiens
    AP2B1
    Mus musculus
    Ap4b1
    Mus musculus
    Ap1b1
    Mus musculus
    Ap2b1
    Mus musculus
    Gm43064
    Rattus norvegicus
    Ap1b1
    Rattus norvegicus
    Ap4b1
    Rattus norvegicus
    Ap2b1
    Schizosaccharomyces pombe
    apl2

    External links

    Saccharomyces Genome Database
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (853723)
    Homologues
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    UniProt
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    Internet
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