DrugAge entry for Zomepirac sodium

Name: Zomepirac sodium
Synonyms: 1H-Pyrrole-2-acetic acid, 5-(4-chlorobenzoyl)-1,4-dimethyl-, sodium salt • 5-(4-Chlorobenzoyl)-1,4-dimethyl-1H-pyrrole-2-acetic acid sodium salt • 64092-48-4 • CAS-64092-48-4 • DA5B6IWF46 • DSSTox_CID_13989 • DSSTox_GSID_33989 • DSSTox_RID_79106 • EINECS 264-669-2 • McN 2783-21-98 • MLS001055441 • NCGC00090751-01 • NCGC00094811-01 • Prestwick_973 • SMR000686071 • Sodium 5-(4-chlorobenzoyl)-1,4-dimethyl-1H-pyrrole-2-acetate • Sodium zomepirac • sodium;2-[5-(4-chlorobenzoyl)-1,4-dimethylpyrrol-2-yl]acetate • UNII-DA5B6IWF46 • Zomax • Zomepirac (sodium salt) • ZOMEPIRAC SODIUM • Zomepirac sodium anhydrous • Zomepirac sodium salt • ZOMEPIRACSODIUMSALT
CAS Number
IUPAC Name: sodium;2-[5-(4-chlorobenzoyl)-1,4-dimethylpyrrol-2-yl]acetate
PubChem CID: 16220118

Summary

Species	No. Entries	MAX(Avg/Med Lifespan Change %)	MEAN(Avg/Med Lifespan Change %)	MAX(Max Lifespan Change %)	MEAN(Max Lifespan Change %)

Results

Compound/Formulation	Species	Sex	Strain	Dosage	Avg/Med Lifespan Change (%)	Avg/Med Lifespan Significance	Max Lifespan Change (%)	Reference

Lifespan Charts for Zomepirac sodium

Average/Median Lifespan
Max Lifespan
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References

Lombard, DB et al. (2020) High-throughput small molecule screening reveals Nrf2-dependent and -independent pathways of cellular stress resistance. Sci Adv 6(40) PubMed

DGIdb Human Drug-Gene Interactions for Zomepirac sodium

Interaction Types	Gene Symbol	Common Name	HGNC Id	DGIdb Sources	References

Stitch DB Human Drug-Protein Interactions for Zomepirac sodium

Up to 20 direct protein and drug interactions are displayed, having a medium confidence score (0.450) or above. Second order interactions are tabulated below.

Ensembl Id	StringDB Id