DrugAge entry for Ziprasidone hydrochloride monohydrate

Name: Ziprasidone hydrochloride monohydrate
Synonyms: 138982-67-9 • 138982-67-9 (HCl hydrate) • 216X081ORU • 2H-Indol-2-one, 5-[2-[4-(1,2-benzisothiazol-3-yl)-1-piperazinyl]ethyl]-6-chloro-1,3-dihydro-, hydrochloride, hydrate (1:1:1) • 5-(2-(4-(Benzo[d]isothiazol-3-yl)piperazin-1-yl)ethyl)-6-chloroindolin-2-one hydrochloride hydrate • 5-[2-[4-(1,2-Benzisothiazol-3-yl)-1-piperazinyl]ethyl]-6-chloro-1,3-dihydro-2H-indol-2-one hydrochloride monohydrate • 5-[2-[4-(1,2-Benzisothiazol-3yl)-1-piperazinyl]ethyl]-6-chloro-1,3-dihydro-2H-indol-2-one hydrochloride • 5-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]-6-chloro-1,3-dihydroindol-2-one;hydrate;hydrochloride • CHEBI:32314 • CP 88,059-1 • CP-88,059-1 • CP-88059-1 • CP-880591 • Geodon • Geodon (TN) • MFCD00921885 • NCGC00186050-01 • UNII-216X081ORU • Zeldox • Ziprasidone (hydrochloride monohydrate) • Ziprasidone HCl hydrate • ZIPRASIDONE HYDROCHLORIDE HYDRATE • Ziprasidone hydrochloride monohydrate • Ziprasidone hydrochloride [USAN:USP] • zlchem 4
CAS Number: 138982-67-9
IUPAC Name: 5-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]-6-chloro-1,3-dihydroindol-2-one;hydrate;hydrochloride
PubChem CID: 60853

Summary

Species	No. Entries	MAX(Avg/Med Lifespan Change %)	MEAN(Avg/Med Lifespan Change %)	MAX(Max Lifespan Change %)	MEAN(Max Lifespan Change %)

Results

Compound/Formulation	Species	Sex	Strain	Dosage	Avg/Med Lifespan Change (%)	Avg/Med Lifespan Significance	Max Lifespan Change (%)	Reference

Lifespan Charts for Ziprasidone hydrochloride monohydrate

Average/Median Lifespan
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References

Lombard, DB et al. (2020) High-throughput small molecule screening reveals Nrf2-dependent and -independent pathways of cellular stress resistance. Sci Adv 6(40) PubMed

DGIdb Human Drug-Gene Interactions for Ziprasidone hydrochloride monohydrate

Interaction Types	Gene Symbol	Common Name	HGNC Id	DGIdb Sources	References

Stitch DB Human Drug-Protein Interactions for Ziprasidone hydrochloride monohydrate

Up to 20 direct protein and drug interactions are displayed, having a medium confidence score (0.450) or above. Second order interactions are tabulated below.

Ensembl Id	StringDB Id