DrugAge entry for Xanthine

Name: Xanthine
Synonyms: 1H-Purine-2,6(3H,7H)-dione • 1H-Purine-2,6-diol • 1H-Purine-2,6-dione, 3,7-dihydro- • 1H-Purine-2,6-dione, 3,9-dihydro- • 2,6(1,3)-Purinedion • 2,6-Dihydroxypurine • 2,6-Dioxo-1,2,3,6-tetrahydropurine • 2,6-dioxopurine • 3,7-Dihydro-1H-purine-2,6-dione • 3,7-dihydropurine-2,6-dione • 3,9-dihydro-1H-purine-2,6-dione • 69-89-6 • 9H-Purine-2,6-(1H,3H)-dione • 9H-Purine-2,6-diol • 9H-xanthine • Isoxanthine • Pseudoxanthine • Purine-2(3H),6(1H)-dione • Purine-2,6-(1H,3H)-dione • Purine-2,6-diol • USAF CB-17 • XAN • Xanthic oxide • Xanthin • xanthine
CAS Number
IUPAC Name: 3,7-dihydropurine-2,6-dione
PubChem CID

Summary

Species	No. Entries	MAX(Avg/Med Lifespan Change %)	MEAN(Avg/Med Lifespan Change %)	MAX(Max Lifespan Change %)	MEAN(Max Lifespan Change %)

Results

Compound/Formulation	Species	Sex	Strain	Dosage	Avg/Med Lifespan Change (%)	Avg/Med Lifespan Significance	Max Lifespan Change (%)	Reference

Lifespan Charts for Xanthine

Average/Median Lifespan
Max Lifespan
Hide Charts

References

Du X, et al. (2018) Low Concentrations of Caffeine and Its Analogs Extend the Lifespan of Caenorhabditis elegans by Modulating IGF-1-Like Pathway Frontiers in ageing neuroscience () PubMed
Harold R Massie (1991) Uric acid content of Drosophila decreases with aging Experimental Gerontology 26(6)609-614 PubMed

DGIdb Human Drug-Gene Interactions for Xanthine

Interaction Types	Gene Symbol	Common Name	HGNC Id	DGIdb Sources	References

Stitch DB Human Drug-Protein Interactions for Xanthine

Up to 20 direct protein and drug interactions are displayed, having a medium confidence score (0.450) or above. Second order interactions are tabulated below.

Ensembl Id	StringDB Id