DrugAge entry for Vinblastine Sulfate

Name: Vinblastine Sulfate
Synonyms: 143-67-9 • 29060 LE • Belvan, VLB • CHEBI:9984 • Exal (TN) • MFCD00082457 • MFCD08706468 • NSC 49842 • NSC49842 • Velban (TN) • Velban (TN) (Lilly) • Vinblastine 5 • Vinblastine Sulfate Hydrate • Vinblastine sulphate • Vinblastine, hydrate • Vincaleucoblastine sulfate • Vincaleukoblastine sulfate • Vincaleukoblastine sulfate (1:1) (salt) • Vincaleukoblastine, hydrate • VLB monosulfate
CAS Number
IUPAC Name: methyl (1R,9R,10S,11R,12R,19R)-11-acetyloxy-12-ethyl-4-[(13S,15S,17S)-17-ethyl-17-hydroxy-13-methoxycarbonyl-1,11-diazatetracyclo[13.3.1.04,12.05,10]nonadeca-4(12),5,7,9-tetraen-13-yl]-10-hydroxy-5-methoxy-8-methyl-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2,4,6,13-tetraene-10-carboxylate;sulfuric acid
PubChem CID: 241902

Summary

Species	No. Entries	MAX(Avg/Med Lifespan Change %)	MEAN(Avg/Med Lifespan Change %)	MAX(Max Lifespan Change %)	MEAN(Max Lifespan Change %)

Results

Compound/Formulation	Species	Sex	Strain	Dosage	Avg/Med Lifespan Change (%)	Avg/Med Lifespan Significance	Max Lifespan Change (%)	Reference

Lifespan Charts for Vinblastine Sulfate

Average/Median Lifespan
Max Lifespan
Hide Charts

References

Lombard, DB et al. (2020) High-throughput small molecule screening reveals Nrf2-dependent and -independent pathways of cellular stress resistance. Sci Adv 6(40) PubMed

DGIdb Human Drug-Gene Interactions for Vinblastine Sulfate

Interaction Types	Gene Symbol	Common Name	HGNC Id	DGIdb Sources	References

Stitch DB Human Drug-Protein Interactions for Vinblastine Sulfate

Up to 20 direct protein and drug interactions are displayed, having a medium confidence score (0.450) or above. Second order interactions are tabulated below.

Ensembl Id	StringDB Id