DrugAge entry for Uric acid

Name: Uric acid
Synonyms: 1H-Purine-2,6,8(3H)-trione, 7,9-dihydro- • 1H-Purine-2,6,8-triol • 2,3,6,7,8,9-hexahydro-1H-purine-2,6,8-trione • 2,6,8-trihydroxypurine • 2,6,8-Trioxopurine • 2,6,8-trioxypurine • 69-93-2 • 7,9-Dihydro-1H-purine-2,6,8(3H)-trione • 7,9-dihydro-3H-purine-2,6,8-trione • 8-hydroxyxanthine • 9H-purine-2,6,8-triol • AI3-15432 • CHEMBL792 • Lithic acid • MFCD00005712 • NSC 3975 • Purine-2,6,8(1H,3H,9H)-trione • trioxopurine • UNII-268B43MJ25 • urate
CAS Number: 69-93-2
IUPAC Name: 7,9-dihydro-3H-purine-2,6,8-trione
PubChem CID: 1175

Summary

Species	No. Entries	MAX(Avg/Med Lifespan Change %)	MEAN(Avg/Med Lifespan Change %)	MAX(Max Lifespan Change %)	MEAN(Max Lifespan Change %)

Results

Compound/Formulation	Species	Sex	Strain	Dosage	Avg/Med Lifespan Change (%)	Avg/Med Lifespan Significance	Max Lifespan Change (%)	Reference

Lifespan Charts for Uric acid

Average/Median Lifespan
Max Lifespan
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References

Wan, QL et al. (2020) Uric acid induces stress resistance and extends the life span through activating the stress response factor DAF-16/FOXO and SKN-1/NRF2. Aging (Albany NY) 12(3)2840-2856 PubMed

DGIdb Human Drug-Gene Interactions for Uric acid

Interaction Types	Gene Symbol	Common Name	HGNC Id	DGIdb Sources	References

Stitch DB Human Drug-Protein Interactions for Uric acid

Up to 20 direct protein and drug interactions are displayed, having a medium confidence score (0.450) or above. Second order interactions are tabulated below.

Ensembl Id	StringDB Id