DrugAge entry for Uracil

Name: Uracil
Synonyms: 1,2,3,4-tetrahydropyrimidine-2,4-dione • 1H-Pyrimidine-2,4-dione • 2,4(1H,3H)-Pyrimidinedione • 2,4-Dihydroxypyrimidine • 2,4-Dioxopyrimidine • 2,4-Pyrimidinediol • 2,4-Pyrimidinedione • 51953-14-1 • 66-22-8 • CCRIS 3077 • Hybar X • MFCD00006016 • Pirod • pyrimidine-2,4(1H,3H)-dione • pyrimidine-2,4-diol • Pyrod • RU 12709 • Ura • Uracil [USAN] • Uracyl
CAS Number: 66-22-8
IUPAC Name: 1H-pyrimidine-2,4-dione
PubChem CID: 1174

Summary

Species	No. Entries	MAX(Avg/Med Lifespan Change %)	MEAN(Avg/Med Lifespan Change %)	MAX(Max Lifespan Change %)	MEAN(Max Lifespan Change %)

Results

Compound/Formulation	Species	Sex	Strain	Dosage	Avg/Med Lifespan Change (%)	Avg/Med Lifespan Significance	Max Lifespan Change (%)	Reference

Lifespan Charts for Uracil

Average/Median Lifespan
Max Lifespan
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References

Wan, QL et al. (2019) Intermediate metabolites of the pyrimidine metabolism pathway extend the lifespan of Aging (Albany NY) 11(12)3993-4010 PubMed

DGIdb Human Drug-Gene Interactions for Uracil

Interaction Types	Gene Symbol	Common Name	HGNC Id	DGIdb Sources	References

Stitch DB Human Drug-Protein Interactions for Uracil

Up to 20 direct protein and drug interactions are displayed, having a medium confidence score (0.450) or above. Second order interactions are tabulated below.

Ensembl Id	StringDB Id