DrugAge entry for URB597

Name: URB597
Synonyms: 3'-Carbamoyl-[1,1'-biphenyl]-3-yl cyclohexylcarbamate • 3'-Carbamoylbiphenyl-3-yl cyclohexylcarbamate • 3-(3-carbamoylphenyl)phenyl N-cyclohexylcarbamate • 546141-08-6 • C20H22N2O3 • CARBAMIC ACID, CYCLOHEXYL-, 3'-(AMINOCARBONYL)[1,1'-BIPHENYL]-3-YL ESTER • Carbamic acid, N-cyclohexyl-, 3'-(aminocarbonyl)[1,1'-biphenyl]-3-yl ester • CHEMBL184238 • Cyclohexyl-carbamic acid 3'-carbamoyl-biphenyl-3-yl ester • FAAH Inhibitor II • KDS-4103 • MFCD05863934 • PX47LB88FO • SMR000524783 • SR-01000342602 • UNII-PX47LB88FO • URB 597 • URB-597 • URB597 (KDS-4103) • [3-(3-carbamoylphenyl)phenyl] N-cyclohexylcarbamate
CAS Number: 546141-08-6
IUPAC Name: [3-(3-carbamoylphenyl)phenyl] N-cyclohexylcarbamate
PubChem CID: 1383884

Summary

Species	No. Entries	MAX(Avg/Med Lifespan Change %)	MEAN(Avg/Med Lifespan Change %)	MAX(Max Lifespan Change %)	MEAN(Max Lifespan Change %)

Results

Compound/Formulation	Species	Sex	Strain	Dosage	Avg/Med Lifespan Change (%)	Avg/Med Lifespan Significance	Max Lifespan Change (%)	Reference

Lifespan Charts for URB597

Average/Median Lifespan
Max Lifespan
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References

Chen, AL et al. (2019) Pharmacological convergence reveals a lipid pathway that regulates C. elegans lifespan. Nat Chem Biol 15(5)453-462 PubMed

DGIdb Human Drug-Gene Interactions for URB597

Interaction Types	Gene Symbol	Common Name	HGNC Id	DGIdb Sources	References

Stitch DB Human Drug-Protein Interactions for URB597

Up to 20 direct protein and drug interactions are displayed, having a medium confidence score (0.450) or above. Second order interactions are tabulated below.

Ensembl Id	StringDB Id