DrugAge entry for Trilobatin

Name: Trilobatin
Synonyms: 1-(2,6-dihydroxy-4-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)phenyl)-3-(4-hydroxyphenyl)propan-1-one • 1-[2,6-dihydroxy-4-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]-3-(4-hydroxyphenyl)propan-1-one • 23298I791N • 3,5-dihydroxy-4-[3-(4-hydroxyphenyl)propanoyl]phenyl beta-D-glucopyranoside • 4192-90-9 • ACon1_000618 • AKOS032948098 • BDBM50256748 • CHEBI:145829 • CHEMBL514177 • DTXSID10194681 • HY-N4100 • MEGxp0_002006 • p-Phloridzin • p-Phlorizin • phloretin 4'-glucoside • phloretin-4'-beta-D-glucopyranoside • phloretin-4'-beta-D-glucoside • phloretin-4'-O-glucoside • Phloretin-4-O-glucoside • s9064 • SCHEMBL1144758 • Trilobatin • UNII-23298I791N • ZINC31166407
CAS Number: 4192-90-9
IUPAC Name: 1-[2,6-dihydroxy-4-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]-3-(4-hydroxyphenyl)propan-1-one
PubChem CID: 6451798

Summary

Species	No. Entries	MAX(Avg/Med Lifespan Change %)	MEAN(Avg/Med Lifespan Change %)	MAX(Max Lifespan Change %)	MEAN(Max Lifespan Change %)

Results

Compound/Formulation	Species	Sex	Strain	Dosage	Avg/Med Lifespan Change (%)	Avg/Med Lifespan Significance	Max Lifespan Change (%)	Reference

Lifespan Charts for Trilobatin

Average/Median Lifespan
Max Lifespan
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References

Li, N et al. (2021) Trilobatin, a Component from Front Pharmacol 12()655045 PubMed

DGIdb Human Drug-Gene Interactions for Trilobatin

Interaction Types	Gene Symbol	Common Name	HGNC Id	DGIdb Sources	References

Stitch DB Human Drug-Protein Interactions for Trilobatin

Up to 20 direct protein and drug interactions are displayed, having a medium confidence score (0.450) or above. Second order interactions are tabulated below.

Ensembl Id	StringDB Id