DrugAge entry for Triiodothyronine

Name: Triiodothyronine
Synonyms: (2S)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]propanoic acid • (S)-2-amino-3-(4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl)propanoic acid • 03/02/6893 • 3,3',5-Triiodo-L-thyronine • 3,3',5-Triiodothyronine • 3,5,3'-Triiodo-L-thyronine • 3,5,3'-triiodothyronine • 3,5,3'TRIIODOTHYRONINE • 6893-02-3 • CHEBI:18258 • L-3,3',5-TriioDOThyronine • L-3,5,3'-Triiodothyronine • L-Liothyronine • L-T3 • L-Tyrosine, O-(4-hydroxy-3-iodophenyl)-3,5-diiodo- • Liothyronin • liothyronine • Liothyroninum • Liotironina • MFCD00002593 • O-(4-Hydroxy-3-iodophenyl)-3,5-diiodo-L-tyrosine • T3 • Tresitope • Triiodo-L-thyronine • triiodothyronine • triothyrone
CAS Number: 6893-02-3
IUPAC Name: (2S)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]propanoic acid
PubChem CID: 5920

Summary

Species	No. Entries	MAX(Avg/Med Lifespan Change %)	MEAN(Avg/Med Lifespan Change %)	MAX(Max Lifespan Change %)	MEAN(Max Lifespan Change %)

Results

Compound/Formulation	Species	Sex	Strain	Dosage	Avg/Med Lifespan Change (%)	Avg/Med Lifespan Significance	Max Lifespan Change (%)	Reference

Lifespan Charts for Triiodothyronine

Average/Median Lifespan
Max Lifespan
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References

Mohanty, SK and Suchiang, K (2021) Triiodothyronine (T3) enhances lifespan and protects against oxidative stress via activation of Klotho in Caenorhabditis elegans. Biogerontology () PubMed

DGIdb Human Drug-Gene Interactions for Triiodothyronine

Interaction Types	Gene Symbol	Common Name	HGNC Id	DGIdb Sources	References

Stitch DB Human Drug-Protein Interactions for Triiodothyronine

Up to 20 direct protein and drug interactions are displayed, having a medium confidence score (0.450) or above. Second order interactions are tabulated below.

Ensembl Id	StringDB Id