DrugAge entry for Tiapride Hydrochloride

Name: Tiapride Hydrochloride
Synonyms: 25N106WEDO • 51012-33-0 • 51012-33-0 (HCl) • Benzamide, N-[2-(diethylamino)ethyl]-2-methoxy-5-(methylsulfonyl)-,monohydrochloride • C15H25ClN2O4S • CAS-51012-33-0 • DSSTox_CID_25210 • DSSTox_GSID_45210 • DSSTox_RID_80753 • Gramalil • MFCD00133861 • MLS000069678 • N-(2-(Diethylamino)ethyl)-2-methoxy-5-(methylsulfonyl)benzamide hydrochloride • N-(2-(Diethylamino)ethyl)-2-methoxy-5-(methylsulphonyl)benzamide monohydrochloride • N-(2-[Diethylamino]ethyl)-5-(methylsulfonyl)-o-anisamide hydrochloride • N-[2-(Diethylamino)ethyl]-2-methoxy-5-(methylsulfonyl)benzamide Hydrochloride • N-[2-(Diethylamino)ethyl]-5-(methylsulfonyl)-o-anisamide hydrochloride • NCGC00015996-02 • SMR000058514 • SR-01000000232 • Tiapridal • Tiapride (hydrochloride) • Tiapride HCl • Tiapride hydrochloride • UNII-25N106WEDO
CAS Number: 51012-33-0
IUPAC Name: N-[2-(diethylamino)ethyl]-2-methoxy-5-methylsulfonylbenzamide;hydrochloride
PubChem CID: 5702214

Summary

Species	No. Entries	MAX(Avg/Med Lifespan Change %)	MEAN(Avg/Med Lifespan Change %)	MAX(Max Lifespan Change %)	MEAN(Max Lifespan Change %)

Results

Compound/Formulation	Species	Sex	Strain	Dosage	Avg/Med Lifespan Change (%)	Avg/Med Lifespan Significance	Max Lifespan Change (%)	Reference

Lifespan Charts for Tiapride Hydrochloride

Average/Median Lifespan
Max Lifespan
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References

Lombard, DB et al. (2020) High-throughput small molecule screening reveals Nrf2-dependent and -independent pathways of cellular stress resistance. Sci Adv 6(40) PubMed

DGIdb Human Drug-Gene Interactions for Tiapride Hydrochloride

Interaction Types	Gene Symbol	Common Name	HGNC Id	DGIdb Sources	References

Stitch DB Human Drug-Protein Interactions for Tiapride Hydrochloride

Up to 20 direct protein and drug interactions are displayed, having a medium confidence score (0.450) or above. Second order interactions are tabulated below.

Ensembl Id	StringDB Id