DrugAge entry for Thyroxin

Name: Thyroxin
Synonyms: (-)-Thyroxine • 3,3',5,5'-Tetraiodo-L-thyronine • 3,5,3',5'-Tetraiodo-L-thyronine • 51-48-9 • DL-Thyroxin • eltroxin • L-T4 • L-Thyroxin • L-thyroxine • levothroid • Levothyroxin • levothyroxine • Levothyroxine sodium • Levoxyl • synthroid • Tetraiodothyronine • Thyratabs • Thyrax • Thyreoideum • thyroxin • Thyroxinal • thyroxine • Thyroxine (l) • Thyroxine (VAN) • Thyroxine iodine
CAS Number: 51-48-9
IUPAC Name: (2S)-2-amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]propanoic acid
PubChem CID: 5819
SEP-L1000 side effects: Abdominal pain, Asthenia, Ataxia, Diarrhoea, Dizziness, Dyspepsia, Erythema, Hypersensitivity, Hypertension, Hypotension, Nausea, Oedema, Pain, Pruritus, Rash, Somnolence, Urticaria, Vomiting

Summary

Species	No. Entries	MAX(Avg/Med Lifespan Change %)	MEAN(Avg/Med Lifespan Change %)	MAX(Max Lifespan Change %)	MEAN(Max Lifespan Change %)

Results

Compound/Formulation	Species	Sex	Strain	Dosage	Avg/Med Lifespan Change (%)	Avg/Med Lifespan Significance	Max Lifespan Change (%)	Reference

Lifespan Charts for Thyroxin

Average/Median Lifespan
Max Lifespan
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References

Ooka, H et al. (1983) Pituitary-thyroid activity and longevity in neonatally thyroxine-treated rats. Mech. Ageing Dev. 22(2)113-120 PubMed

DGIdb Human Drug-Gene Interactions for Thyroxin

Interaction Types	Gene Symbol	Common Name	HGNC Id	DGIdb Sources	References

Stitch DB Human Drug-Protein Interactions for Thyroxin

Up to 20 direct protein and drug interactions are displayed, having a medium confidence score (0.450) or above. Second order interactions are tabulated below.

Ensembl Id	StringDB Id