DrugAge entry for Thyroxin

Name
Thyroxin 
Synonyms
(-)-Thyroxine • 3,3',5,5'-Tetraiodo-L-thyronine • 3,5,3',5'-Tetraiodo-L-thyronine • 51-48-9 • DL-Thyroxin • eltroxin • L-T4 • L-Thyroxin • L-thyroxine • levothroid • Levothyroxin • levothyroxine • Levothyroxine sodium • Levoxyl • synthroid • Tetraiodothyronine • Thyratabs • Thyrax • Thyreoideum • thyroxin • Thyroxinal • thyroxine • Thyroxine (l) • Thyroxine (VAN) • Thyroxine iodine 
CAS Number
51-48-9 
IUPAC Name
(2S)-2-amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]propanoic acid 
PubChem CID
5819 
SEP-L1000 side effects
Abdominal pain, Asthenia, Ataxia, Diarrhoea, Dizziness, Dyspepsia, Erythema, Hypersensitivity, Hypertension, Hypotension, Nausea, Oedema, Pain, Pruritus, Rash, Somnolence, Urticaria, Vomiting 

Summary

Species No. Entries MAX(Avg Lifespan Change %) MAX(Max Lifespan Change %)

Results

Compound/Formulation Species Avg/Med Lifespan Change (%) Max Lifespan Change (%) Strain Dosage Significant? Reference

Lifespan Charts for Thyroxin


References

Ooka, H et al. (1983) Pituitary-thyroid activity and longevity in neonatally thyroxine-treated rats. Mech. Ageing Dev. 22(2)113-120 PubMed

DGIdb Human Drug-Gene Interactions for Thyroxin

Interaction Types Gene Symbol Common Name Entrez Id DGIdb Sources Homologs References

Stitch DB Human Drug-Protein Interactions for Thyroxin

Up to 20 direct protein and drug interactions are displayed, having a medium confidence score (0.450) or above. Second order interactions are tabulated below.

Ensembl Id StringDB Id