DrugAge entry for Thymine

Name: Thymine
Synonyms: 2,4(1H,3H)-Pyrimidinedione, 5-methyl- • 2,4-Dihydroxy-5-methylpyrimidine • 4-Hydroxy-5-methylpyrimidin-2(1H)-one • 5-Methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione • 5-methyl-1H-pyrimidine-2,4-dione • 5-methyl-2,4(1H,3H)-pyrimidinedione • 5-methylpyrimidine-2,4(1H,3H)-dione • 5-methylpyrimidine-2,4-diol • 5-Methylpyrimidine-2,4-dione • 5-methyluracil • 65-71-4 • AI3-25479 • CCRIS 5584 • CHEBI:17821 • MFCD00006026 • NSC14705 • Thymin • Thymin (purine base) • Thymine anhydrate • UNII-QR26YLT7LT
CAS Number: 65-71-4
IUPAC Name: 5-methyl-1H-pyrimidine-2,4-dione
PubChem CID: 1135

Summary

Species	No. Entries	MAX(Avg/Med Lifespan Change %)	MEAN(Avg/Med Lifespan Change %)	MAX(Max Lifespan Change %)	MEAN(Max Lifespan Change %)

Results

Compound/Formulation	Species	Sex	Strain	Dosage	Avg/Med Lifespan Change (%)	Avg/Med Lifespan Significance	Max Lifespan Change (%)	Reference

Lifespan Charts for Thymine

Average/Median Lifespan
Max Lifespan
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References

Wan, QL et al. (2019) Intermediate metabolites of the pyrimidine metabolism pathway extend the lifespan of Aging (Albany NY) 11(12)3993-4010 PubMed

DGIdb Human Drug-Gene Interactions for Thymine

Interaction Types	Gene Symbol	Common Name	HGNC Id	DGIdb Sources	References

Stitch DB Human Drug-Protein Interactions for Thymine

Up to 20 direct protein and drug interactions are displayed, having a medium confidence score (0.450) or above. Second order interactions are tabulated below.

Ensembl Id	StringDB Id