DrugAge entry for Thioflavin T

Name: Thioflavin T
Synonyms: 2-(4-(Dimethylamino)phenyl)-3,6-dimethylbenzo[d]thiazol-3-ium chloride • 2390-54-7 • Acronol Yellow T • Acronol Yellow TC • Basic yellow 1 • Basic Yellow T • Brilliant Flavine T • C.I. Basic Yellow 1 • Citroflavine 8G • Methylene Yellow N • Methylene Yellow NI • Primoflavine 8G • Purimofurabin 8G • Rhoduline Yellow • Setoflavin T • Setoflavine T • Tannoflavine T • thioflavin S • Thioflavin T • Thioflavin TCN • Thioflavin TG • Thioflavine T • Thioflavine TCN • Thioflavine TCND • Thioflavine TG
CAS Number: 2390-54-7
IUPAC Name: 4-(3,6-dimethyl-1,3-benzothiazol-3-ium-2-yl)-N,N-dimethylaniline;chloride
PubChem CID: 16953

Summary

Species	No. Entries	MAX(Avg/Med Lifespan Change %)	MEAN(Avg/Med Lifespan Change %)	MAX(Max Lifespan Change %)	MEAN(Max Lifespan Change %)

Results

Compound/Formulation	Species	Sex	Strain	Dosage	Avg/Med Lifespan Change (%)	Avg/Med Lifespan Significance	Max Lifespan Change (%)	Reference

Lifespan Charts for Thioflavin T

Average/Median Lifespan
Max Lifespan
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References

Alavez, S et al. (2011) Amyloid-binding compounds maintain protein homeostasis during ageing and extend lifespan. Nature 472(7342)226-229 PubMed
Banse, SA et al. (2019) Automated lifespan determination across Caenorhabditis strains and species reveals assay-specific effects of chemical interventions. Geroscience 41(6)945-960 PubMed

DGIdb Human Drug-Gene Interactions for Thioflavin T

Interaction Types	Gene Symbol	Common Name	HGNC Id	DGIdb Sources	References

Stitch DB Human Drug-Protein Interactions for Thioflavin T

Up to 20 direct protein and drug interactions are displayed, having a medium confidence score (0.450) or above. Second order interactions are tabulated below.

Ensembl Id	StringDB Id