DrugAge entry for Theobromine

Name: Theobromine
Synonyms: 1H-Purine-2,6-dione, 3,7-dihydro-3,7-dimethyl- • 2,6-Dihydroxy-3,7-dimethylpurine • 3,7-Dihydro-3,7-dimethyl-1H-purine-2,6-dione • 3,7-Dimethyl-3,7-dihydro-1H-purine-2,6-dione • 3,7-dimethylpurine-2,6-dione • 3,7-Dimethylxanthine • 83-67-0 • Diurobromine • FEMA No. 3591 • MFCD00022830 • Santheose • SC 15090 • Teobromin • Theobromin • Theosalvose • Theostene • Thesal • Thesodate • UNII-OBD445WZ5P • Xanthine, 3,7-dimethyl-
CAS Number: 83-67-0
IUPAC Name: 3,7-dimethylpurine-2,6-dione
PubChem CID: 5429

Summary

Species	No. Entries	MAX(Avg/Med Lifespan Change %)	MEAN(Avg/Med Lifespan Change %)	MAX(Max Lifespan Change %)	MEAN(Max Lifespan Change %)

Results

Compound/Formulation	Species	Sex	Strain	Dosage	Avg/Med Lifespan Change (%)	Avg/Med Lifespan Significance	Max Lifespan Change (%)	Reference

Lifespan Charts for Theobromine

Average/Median Lifespan
Max Lifespan
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References

Li, H et al. (2019) Pro-oxidant and lifespan extension effects of caffeine and related methylxanthines in Food Chem X 1()100005 PubMed

DGIdb Human Drug-Gene Interactions for Theobromine

Interaction Types	Gene Symbol	Common Name	HGNC Id	DGIdb Sources	References

Stitch DB Human Drug-Protein Interactions for Theobromine

Up to 20 direct protein and drug interactions are displayed, having a medium confidence score (0.450) or above. Second order interactions are tabulated below.

Ensembl Id	StringDB Id