DrugAge entry for Tetracaine HCl

Name: Tetracaine HCl
Synonyms: 136-47-0 • 2-(dimethylamino)ethyl 4-(butylamino)benzoate hydrochloride • 2-(Dimethylamino)ethyl p-(butylamino)benzoate monohydrochloride • 4-(Butylamino)benzoic Acid 2-(Dimethylamino)ethyl Ester Hydrochloride • 5NF5D4OPCI • Amethocaine hydrochloride • Anethain • Anethaine • Benzoic acid, 4-(butylamino)-, 2-(dimethylamino)ethyl ester, monohydrochloride • Butethanol • Butylocaine • Curtacain • Decicain • Decicaine • Dessicain • Dicainum • Intercaine • MFCD00038912 • MLS000069780 • Tetracaine (hydrochloride) • Tetracaine HCl • Tetracaine hydrochloride • Tetracaine hydrochloride (Pontocaine) • Tetracaine, HCl • tetracainehydrochloride • UNII-5NF5D4OPCI
CAS Number: 136-47-0
IUPAC Name: 2-(dimethylamino)ethyl 4-(butylamino)benzoate;hydrochloride
PubChem CID: 8695

Summary

Species	No. Entries	MAX(Avg/Med Lifespan Change %)	MEAN(Avg/Med Lifespan Change %)	MAX(Max Lifespan Change %)	MEAN(Max Lifespan Change %)

Results

Compound/Formulation	Species	Sex	Strain	Dosage	Avg/Med Lifespan Change (%)	Avg/Med Lifespan Significance	Max Lifespan Change (%)	Reference

Lifespan Charts for Tetracaine HCl

Average/Median Lifespan
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References

Lombard, DB et al. (2020) High-throughput small molecule screening reveals Nrf2-dependent and -independent pathways of cellular stress resistance. Sci Adv 6(40) PubMed

DGIdb Human Drug-Gene Interactions for Tetracaine HCl

Interaction Types	Gene Symbol	Common Name	HGNC Id	DGIdb Sources	References

Stitch DB Human Drug-Protein Interactions for Tetracaine HCl

Up to 20 direct protein and drug interactions are displayed, having a medium confidence score (0.450) or above. Second order interactions are tabulated below.

Ensembl Id	StringDB Id