DrugAge entry for Supercinnamaldehyde

Name: Supercinnamaldehyde
Synonyms: (3E)-1-methyl-3-(2-oxopropylidene)indol-2-one • 1,3-DIHYDRO-1-METHYL-3-(2-OXOPROPYLIDENE)-2H-INDOL-2-ONE • 70351-51-8 • BDBM50203070 • CHEMBL402589 • GTPL6270 • MFCD08530327 • Q27088897 • SCHEMBL1078803 • super cinnamaldehyde • supercinnamaldehyde • Supercinnamaldehyde, >=98% (HPLC) • ZINC29043655
CAS Number
IUPAC Name: (3E)-1-methyl-3-(2-oxopropylidene)indol-2-one
PubChem CID: 12480411

Summary

Species	No. Entries	MAX(Avg/Med Lifespan Change %)	MEAN(Avg/Med Lifespan Change %)	MAX(Max Lifespan Change %)	MEAN(Max Lifespan Change %)

Results

Compound/Formulation	Species	Sex	Strain	Dosage	Avg/Med Lifespan Change (%)	Avg/Med Lifespan Significance	Max Lifespan Change (%)	Reference

Lifespan Charts for Supercinnamaldehyde

Average/Median Lifespan
Max Lifespan
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References

Lombard, DB et al. (2020) High-throughput small molecule screening reveals Nrf2-dependent and -independent pathways of cellular stress resistance. Sci Adv 6(40) PubMed

DGIdb Human Drug-Gene Interactions for Supercinnamaldehyde

Interaction Types	Gene Symbol	Common Name	HGNC Id	DGIdb Sources	References

Stitch DB Human Drug-Protein Interactions for Supercinnamaldehyde

Up to 20 direct protein and drug interactions are displayed, having a medium confidence score (0.450) or above. Second order interactions are tabulated below.

Ensembl Id	StringDB Id