DrugAge entry for Serine

Name: Serine
Synonyms: (-)-Serine • (2S)-2-amino-3-hydroxypropanoic acid • (S)-(-)-Serine • (S)-2-Amino-3-hydroxypropanoic acid • (S)-Serine • 2-Amino-3-hydroxypropionic acid • 56-45-1 • alpha-Amino-beta-hydroxypropionic acid • beta-Hydroxy-L-alanine • beta-Hydroxyalanine • H-Ser-OH • HSDB 680 • L-(-)-Serine • L-2-Amino-3-hydroxypropionic acid • L-3-Hydroxy-2-aminopropionic acid • L-3-Hydroxy-alanine • L-ser • L-Serin • L-serine • SER (IUPAC abbrev) • Serina [Spanish] • serine • Serine (VAN) • Serine, L- • Serinum [Latin]
CAS Number: 56-45-1
IUPAC Name: (2S)-2-amino-3-hydroxypropanoic acid
PubChem CID: 5951

Summary

Species	No. Entries	MAX(Avg/Med Lifespan Change %)	MEAN(Avg/Med Lifespan Change %)	MAX(Max Lifespan Change %)	MEAN(Max Lifespan Change %)

Results

Compound/Formulation	Species	Sex	Strain	Dosage	Avg/Med Lifespan Change (%)	Avg/Med Lifespan Significance	Max Lifespan Change (%)	Reference

Lifespan Charts for Serine

Average/Median Lifespan
Max Lifespan
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References

Edwards, C et al. (2015) Mechanisms of amino acid-mediated lifespan extension in Caenorhabditis elegans. BMC Genet. 16()8 PubMed
Liu, YJ et al. (2019) Glycine promotes longevity in Caenorhabditis elegans in a methionine cycle-dependent fashion. PLoS Genet 15(3)e1007633 PubMed

DGIdb Human Drug-Gene Interactions for Serine

Interaction Types	Gene Symbol	Common Name	HGNC Id	DGIdb Sources	References

Stitch DB Human Drug-Protein Interactions for Serine

Up to 20 direct protein and drug interactions are displayed, having a medium confidence score (0.450) or above. Second order interactions are tabulated below.

Ensembl Id	StringDB Id