DrugAge entry for Scriptaid

Name: Scriptaid
Synonyms: 1h-benz[de]isoquinoline-2(3h)-hexanamide, n-hydroxy-1,3-dioxo- • 287383-59-9 • 6-(1,3-Dioxo-1H,3H-benzo[de]isoquinolin-2-yl)-hexanoic acid hydroxyamide • 6-(1,3-Dioxo-1H-benzo[de]isoquinolin-2(3H)-yl)-N-hydroxyhexanamide • 6-(1,3-dioxobenzo[de]isoquinolin-2-yl)-N-hydroxyhexanamide • CBDivE_004422 • CGK1026 • CHEMBL96051 • EJQ8CD8BSV • GCK 1026 • GNF-PF-2024 • N-Hydroxy-1,3-dioxo-1H-benz(de)isoquinoline-2(3H)-hexan amide • N-Hydroxy-1,3-dioxo-1H-benz[de]isoquinoline-2(3H)-hexanamide • N-Hydroxy-1,3-dioxo-1H-benz[de]isoquinoline-2(3H)-hexananmide • SB-556629 • Scriptaid(GCK1026) • Scriptaid, >=95%, solid • Scriptide • Scriptide;GCK1026 • UNII-EJQ8CD8BSV
CAS Number
IUPAC Name: 6-(1,3-dioxobenzo[de]isoquinolin-2-yl)-N-hydroxyhexanamide
PubChem CID: 5186

Summary

Species	No. Entries	MAX(Avg/Med Lifespan Change %)	MEAN(Avg/Med Lifespan Change %)	MAX(Max Lifespan Change %)	MEAN(Max Lifespan Change %)

Results

Compound/Formulation	Species	Sex	Strain	Dosage	Avg/Med Lifespan Change (%)	Avg/Med Lifespan Significance	Max Lifespan Change (%)	Reference

Lifespan Charts for Scriptaid

Average/Median Lifespan
Max Lifespan
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References

Lombard, DB et al. (2020) High-throughput small molecule screening reveals Nrf2-dependent and -independent pathways of cellular stress resistance. Sci Adv 6(40) PubMed

DGIdb Human Drug-Gene Interactions for Scriptaid

Interaction Types	Gene Symbol	Common Name	HGNC Id	DGIdb Sources	References

Stitch DB Human Drug-Protein Interactions for Scriptaid

Up to 20 direct protein and drug interactions are displayed, having a medium confidence score (0.450) or above. Second order interactions are tabulated below.

Ensembl Id	StringDB Id