DrugAge entry for Sappanone A

Name: Sappanone A
Synonyms: (3E)-3-[(3,4-dihydroxyphenyl)methylene]-2,3-dihydro-7-hydroxy-4H-1-benzopyran-4-one • (3E)-3-[(3,4-dihydroxyphenyl)methylidene]-7-hydroxychromen-4-one • 102067-84-5 • 104778-14-5 • 7-Hydroxy-3-(3,4-dihydroxybenzylidene)-2H-1-benzopyran-4(3H)-one • CHEMBL249002 • J3.589.099H • Q18355119 • SAPPANONE A • SCHEMBL2521583 • ZINC14690904
CAS Number
IUPAC Name: (3E)-3-[(3,4-dihydroxyphenyl)methylidene]-7-hydroxychromen-4-one
PubChem CID: 9817274

Summary

Species	No. Entries	MAX(Avg/Med Lifespan Change %)	MEAN(Avg/Med Lifespan Change %)	MAX(Max Lifespan Change %)	MEAN(Max Lifespan Change %)

Results

Compound/Formulation	Species	Sex	Strain	Dosage	Avg/Med Lifespan Change (%)	Avg/Med Lifespan Significance	Max Lifespan Change (%)	Reference

Lifespan Charts for Sappanone A

Average/Median Lifespan
Max Lifespan
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References

Zhao, J et al. (2020) Beneficial effects of sappanone A on lifespan and thermotolerance in Caenorhabditis elegans. Eur J Pharmacol 888()173558 PubMed

DGIdb Human Drug-Gene Interactions for Sappanone A

Interaction Types	Gene Symbol	Common Name	HGNC Id	DGIdb Sources	References

Stitch DB Human Drug-Protein Interactions for Sappanone A

Up to 20 direct protein and drug interactions are displayed, having a medium confidence score (0.450) or above. Second order interactions are tabulated below.

Ensembl Id	StringDB Id