DrugAge entry for Salsalate

Name: Salsalate
Synonyms: 2-(2-hydroxybenzoyl)oxybenzoic acid • 2-Carboxyphenyl salicylate • 552-94-3 • Benzoic acid, 2-hydroxy-, 2-carboxyphenyl ester • Diacesal • Diplosal • Disalcid • Disalicylic acid • Disalicylsaeure • Disalyl • Nobacid • o-Salicylsalicylic acid • Sal Ester Sal • Salical • Salicylic acid, salicylate • Salicyloylsalicylic acid • Salicylsalicylic acid • Salina • Saloxium • Salsalate • Salysal • Sasapirin • Sasapyrin • sasapyrine • Sasapyrinum
CAS Number: 552-94-3
IUPAC Name: 2-(2-hydroxybenzoyl)oxybenzoic acid
PubChem CID: 5161

Summary

Species	No. Entries	MAX(Avg/Med Lifespan Change %)	MEAN(Avg/Med Lifespan Change %)	MAX(Max Lifespan Change %)	MEAN(Max Lifespan Change %)

Results

Compound/Formulation	Species	Sex	Strain	Dosage	Avg/Med Lifespan Change (%)	Avg/Med Lifespan Significance	Max Lifespan Change (%)	Reference

Lifespan Charts for Salsalate

Average/Median Lifespan
Max Lifespan
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References

Lombard, DB et al. (2020) High-throughput small molecule screening reveals Nrf2-dependent and -independent pathways of cellular stress resistance. Sci Adv 6(40) PubMed

DGIdb Human Drug-Gene Interactions for Salsalate

Interaction Types	Gene Symbol	Common Name	HGNC Id	DGIdb Sources	References

Stitch DB Human Drug-Protein Interactions for Salsalate

Up to 20 direct protein and drug interactions are displayed, having a medium confidence score (0.450) or above. Second order interactions are tabulated below.

Ensembl Id	StringDB Id