DrugAge entry for STX64

Name: STX64
Synonyms: 1ttm • 288628-05-7 • 366037O6O7 • 6-oxo-6,7,8,9,10,11-hexahydrocyclohepta[c]chromen-3-yl sulfamate • 6-oxo-6,7,8,9,10,11-hexahydrocyclohepta[c]chromen-3-yl sulfamate. • 6-OXO-8,9,10,11-TETRAHYDRO-7H-CYCLOHEPTA[C][1]BENZOPYRAN-3-O-SULFAMATE • 667 coumate • 667-Coumate • BN 83495 • BN-83495 • BN83495 • CHEMBL286738 • Irosustat • Irosustat [USAN:INN] • STX 64 • STX-64 • STX64 compound • STX64;BN83495;667-Coumate • Sulfamic acid, 6,7,8,9,10,11-hexahydro-6-oxobenzo[b]cyclohepta[d]pyran-3-yl ester • UNII-366037O6O7
CAS Number: 288628-05-7
IUPAC Name: (6-oxo-8,9,10,11-tetrahydro-7H-cyclohepta[c]chromen-3-yl) sulfamate
PubChem CID: 5287541

Summary

Species	No. Entries	MAX(Avg/Med Lifespan Change %)	MEAN(Avg/Med Lifespan Change %)	MAX(Max Lifespan Change %)	MEAN(Max Lifespan Change %)

Results

Compound/Formulation	Species	Sex	Strain	Dosage	Avg/Med Lifespan Change (%)	Avg/Med Lifespan Significance	Max Lifespan Change (%)	Reference

Lifespan Charts for STX64

Average/Median Lifespan
Max Lifespan
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References

Pérez-Jiménez, MM et al. (2021) Steroid hormones sulfatase inactivation extends lifespan and ameliorates age-related diseases. Nat Commun 12(1)49 PubMed

DGIdb Human Drug-Gene Interactions for STX64

Interaction Types	Gene Symbol	Common Name	HGNC Id	DGIdb Sources	References

Stitch DB Human Drug-Protein Interactions for STX64

Up to 20 direct protein and drug interactions are displayed, having a medium confidence score (0.450) or above. Second order interactions are tabulated below.

Ensembl Id	StringDB Id