DrugAge entry for SKF95282 dimaleate

Name: SKF95282 dimaleate
Synonyms: 104076-39-3 • AKOS024456368 • AL1YII70LM • CAS-104076-39-3 • CCG-222549 • CHEMBL1529009 • DSSTox_CID_25811 • DSSTox_GSID_45811 • DSSTox_RID_81148 • DTXSID7045811 • HMS3263J12 • HMS3412E11 • HMS3676E11 • N-(3-(3-(1-Piperidinylmethyl)phenoxy)propyl)-2-benzothiazolamine dimaleate • N-[3-[3-(1-PIPERIDINYLMETHYL)PHENOXY]PROPYL]-2-BENZOTHIAZOLAMINE DIMALEATE • N-[3-[3-(Piperidin-1-ylmethyl)phenoxy]propyl]-1,3-benzothiazol-2-amine dimaleate salt • NCGC00094486-01 • SKF 95282 dimaleate • SKF-95282 dimaleate salt • SR-01000075175 • Tox21_111285 • Tox21_111285_1 • Tox21_501245 • UNII-AL1YII70LM • Zolantidine dimaleate
CAS Number
IUPAC Name: (Z)-but-2-enedioic acid;N-[3-[3-(piperidin-1-ylmethyl)phenoxy]propyl]-1,3-benzothiazol-2-amine
PubChem CID: 11957725

Summary

Species	No. Entries	MAX(Avg/Med Lifespan Change %)	MEAN(Avg/Med Lifespan Change %)	MAX(Max Lifespan Change %)	MEAN(Max Lifespan Change %)

Results

Compound/Formulation	Species	Sex	Strain	Dosage	Avg/Med Lifespan Change (%)	Avg/Med Lifespan Significance	Max Lifespan Change (%)	Reference

Lifespan Charts for SKF95282 dimaleate

Average/Median Lifespan
Max Lifespan
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References

Lombard, DB et al. (2020) High-throughput small molecule screening reveals Nrf2-dependent and -independent pathways of cellular stress resistance. Sci Adv 6(40) PubMed

DGIdb Human Drug-Gene Interactions for SKF95282 dimaleate

Interaction Types	Gene Symbol	Common Name	HGNC Id	DGIdb Sources	References

Stitch DB Human Drug-Protein Interactions for SKF95282 dimaleate

Up to 20 direct protein and drug interactions are displayed, having a medium confidence score (0.450) or above. Second order interactions are tabulated below.

Ensembl Id	StringDB Id