DrugAge entry for Rizatriptan Benzoate

Name: Rizatriptan Benzoate
Synonyms: 145202-66-0 • 2-(5-((1H-1,2,4-triazol-1-yl)methyl)-1H-indol-3-yl)-N,N-dimethylethan-1-amine benzoate • 2-(5-((1H-1,2,4-TRIAZOL-1-YL)METHYL)-1H-INDOL-3-YL)-N,N-DIMETHYLETHANAMINE BENZOATE • benzoic acid;N,N-dimethyl-2-[5-(1,2,4-triazol-1-ylmethyl)-1H-indol-3-yl]ethanamine • L 705,126 • L 705126 • L-705,126 • Maxalt • Maxalt-MLT • MK 0462 • MK 462 • MK-0462 • MK-462 • N,N-Dimethyl-2-[5-(1,2,4-triazol-1-ylmethyl)-1H-indol-3-yl]ethylamine benzoate • rizatrimptan benzoate • Rizatriptan (benzoate) • Rizatriptan benzoate • Rizatriptan Benzoate (Maxalt) • Rizatriptan benzoate [USAN:USP] • rizatriptan, benzoate • Rizatriptan-d6 Benzoate • rizatriptane benzoate • SCHEMBL41226 • UNII-WR978S7QHH • WR978S7QHH
CAS Number: 145202-66-0
IUPAC Name: benzoic acid;N,N-dimethyl-2-[5-(1,2,4-triazol-1-ylmethyl)-1H-indol-3-yl]ethanamine
PubChem CID: 77997

Summary

Species	No. Entries	MAX(Avg/Med Lifespan Change %)	MEAN(Avg/Med Lifespan Change %)	MAX(Max Lifespan Change %)	MEAN(Max Lifespan Change %)

Results

Compound/Formulation	Species	Sex	Strain	Dosage	Avg/Med Lifespan Change (%)	Avg/Med Lifespan Significance	Max Lifespan Change (%)	Reference

Lifespan Charts for Rizatriptan Benzoate

Average/Median Lifespan
Max Lifespan
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References

Lombard, DB et al. (2020) High-throughput small molecule screening reveals Nrf2-dependent and -independent pathways of cellular stress resistance. Sci Adv 6(40) PubMed

DGIdb Human Drug-Gene Interactions for Rizatriptan Benzoate

Interaction Types	Gene Symbol	Common Name	HGNC Id	DGIdb Sources	References

Stitch DB Human Drug-Protein Interactions for Rizatriptan Benzoate

Up to 20 direct protein and drug interactions are displayed, having a medium confidence score (0.450) or above. Second order interactions are tabulated below.

Ensembl Id	StringDB Id