DrugAge entry for Putrescine

Name: Putrescine
Synonyms: 1,4-butanediamine • 1,4-Butylenediamine • 1,4-Diamino-n-butane • 1,4-diaminobutane • 1,4-Tetramethylenediamine • 110-60-1 • AI3-25444 • BRN 0605282 • butane-1,4-diamine • Butylenediamine • CCRIS 6751 • CHEBI:17148 • CHEMBL46257 • EINECS 203-782-3 • H2N(CH2)4NH2 • KIDHWZJUCRJVML-UHFFFAOYSA-N • MFCD00008235 • NSC 60545 • Putrescin • putrescina • putrescine • Putreszin • Tetramethyldiamine • Tetramethylendiamin • tetramethylenediamine
CAS Number: 110-60-1
IUPAC Name: butane-1,4-diamine
PubChem CID: 1045

Summary

Species	No. Entries	MAX(Avg/Med Lifespan Change %)	MEAN(Avg/Med Lifespan Change %)	MAX(Max Lifespan Change %)	MEAN(Max Lifespan Change %)

Results

Compound/Formulation	Species	Sex	Strain	Dosage	Avg/Med Lifespan Change (%)	Avg/Med Lifespan Significance	Max Lifespan Change (%)	Reference

Lifespan Charts for Putrescine

Average/Median Lifespan
Max Lifespan
Hide Charts

References

Edwards, C et al. (2015) Mechanisms of amino acid-mediated lifespan extension in Caenorhabditis elegans. BMC Genet. 16()8 PubMed
Eisenberg T, et al. (2016) Cardioprotection and lifespan extension by the natural polyamine spermidine Nature Medicine () PubMed

DGIdb Human Drug-Gene Interactions for Putrescine

Interaction Types	Gene Symbol	Common Name	HGNC Id	DGIdb Sources	References

Stitch DB Human Drug-Protein Interactions for Putrescine

Up to 20 direct protein and drug interactions are displayed, having a medium confidence score (0.450) or above. Second order interactions are tabulated below.

Ensembl Id	StringDB Id