DrugAge entry for Pterostilbene

Name: Pterostilbene
Synonyms: (E)-4-(3,5-dimethoxystyryl)phenol • 18259-15-9 • 26R60S6A5I • 3',5'-Dimethoxy-4-stilbenol • 3,5-Dimethoxy-4'-hydroxy-trans-stilbene • 3,5-Dimethoxy-4'-hydroxystilbene • 4'-Hydroxy-3,5-dimethoxy-trans-stilbene • 4-((E)-2-(3,5-dimethoxyphenyl)ethenyl)phenol • 4-(2-(3,5-Dimethoxyphenyl)ethenyl)phenol • 4-(3,5-Dimethoxystyryl)phenol • 4-[(1E)-2-(3,5-Dimethoxyphenyl)ethenyl]phenol • 4-[(E)-2-(3,5-dimethoxyphenyl)ethenyl]phenol • 4-[(E)-2-(3,5-dimethoxyphenyl)vinyl]phenol • 537-42-8 • CHEBI:8630 • CHEMBL83527 • MFCD00238710 • Phenol, 4-[(1E)-2-(3,5-dimethoxyphenyl)ethenyl]- • pterostilben • Pterostilbene • SMR000440694 • trans-1-(3,5-Dimethoxyphenyl)-2-(4-hydroxyphenyl)ethylene • trans-3,5-dimethoxy-4'-hydroxystilbene • trans-pterostilbene • UNII-26R60S6A5I
CAS Number: 537-42-8
IUPAC Name: 4-[(E)-2-(3,5-dimethoxyphenyl)ethenyl]phenol
PubChem CID: 5281727

Summary

Species	No. Entries	MAX(Avg/Med Lifespan Change %)	MEAN(Avg/Med Lifespan Change %)	MAX(Max Lifespan Change %)	MEAN(Max Lifespan Change %)

Results

Compound/Formulation	Species	Sex	Strain	Dosage	Avg/Med Lifespan Change (%)	Avg/Med Lifespan Significance	Max Lifespan Change (%)	Reference

Lifespan Charts for Pterostilbene

Average/Median Lifespan
Max Lifespan
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References

Lombard, DB et al. (2020) High-throughput small molecule screening reveals Nrf2-dependent and -independent pathways of cellular stress resistance. Sci Adv 6(40) PubMed

DGIdb Human Drug-Gene Interactions for Pterostilbene

Interaction Types	Gene Symbol	Common Name	HGNC Id	DGIdb Sources	References

Stitch DB Human Drug-Protein Interactions for Pterostilbene

Up to 20 direct protein and drug interactions are displayed, having a medium confidence score (0.450) or above. Second order interactions are tabulated below.

Ensembl Id	StringDB Id