DrugAge entry for Propantheline Bromide

Name: Propantheline Bromide
Synonyms: (2-Hydroxyethyl)diisopropylmethylammonium bromide xanthene-9-carboxylate • 2-Propanaminium,N-methyl-N-(1-methylethyl)-N-[2-[(9H-xanthen-9-ylcarbonyl)oxy]ethyl]-,bromide • 50-34-0 • 50-34-0 (Br) • Bromure de propantheline [INN-French] • Bromuro de proantelina [INN-Spanish] • CAS-50-34-0 • CCRIS 6271 • DSSTox_CID_3519 • DSSTox_GSID_23519 • DSSTox_RID_77062 • EINECS 200-030-6 • methyl-di(propan-2-yl)-[2-(9H-xanthene-9-carbonyloxy)ethyl]azanium;bromide • MFCD00050291 • MLS000028703 • NCGC00094306-02 • NCI-C56257 • Pro-Banthine • Propantheline (bromide) • PROPANTHELINE BROMIDE • Propanthelini bromidum [INN-Latin] • SMR000058661 • SR-01000003171 • UNII-UX9Z118X9F • UX9Z118X9F
CAS Number: 50-34-0
IUPAC Name: methyl-di(propan-2-yl)-[2-(9H-xanthene-9-carbonyloxy)ethyl]azanium;bromide
PubChem CID: 9279

Summary

Species	No. Entries	MAX(Avg/Med Lifespan Change %)	MEAN(Avg/Med Lifespan Change %)	MAX(Max Lifespan Change %)	MEAN(Max Lifespan Change %)

Results

Compound/Formulation	Species	Sex	Strain	Dosage	Avg/Med Lifespan Change (%)	Avg/Med Lifespan Significance	Max Lifespan Change (%)	Reference

Lifespan Charts for Propantheline Bromide

Average/Median Lifespan
Max Lifespan
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References

Lombard, DB et al. (2020) High-throughput small molecule screening reveals Nrf2-dependent and -independent pathways of cellular stress resistance. Sci Adv 6(40) PubMed

DGIdb Human Drug-Gene Interactions for Propantheline Bromide

Interaction Types	Gene Symbol	Common Name	HGNC Id	DGIdb Sources	References

Stitch DB Human Drug-Protein Interactions for Propantheline Bromide

Up to 20 direct protein and drug interactions are displayed, having a medium confidence score (0.450) or above. Second order interactions are tabulated below.

Ensembl Id	StringDB Id