DrugAge entry for Phosphatidylserine

Name: Phosphatidylserine
Synonyms: (2S)-2-Amino-3-((((R)-2,3-bis(stearoyloxy)propoxy)(hydroxy)phosphoryl)oxy)propanoic acid • (2S)-2-Amino-3-((((R)-2,3-bis(stearoyloxy)propoxy)-(hydroxy)phosphoryl)oxy)propanoic acid • 1,2-dioctadecanoyl-sn-glycero-3-phosphoserine • 1,2-distearoyl-sn-glycero-3-phospho-l-serine • 1,2-distearoyl-sn-glycero-3-phosphoserine • 394XK0IH40 • 51446-62-9 • Dioctadecanoylphosphatidylserine • Distearoyl phosphatidylserine • Distearoylphosphatidylserine • L-Serine, 2,3-bis[(1-oxooctadecyl)oxy]propyl ester, dihydrogen phosphate (ester), (R)- • O-[(R)-{[(2r)-2,3-Bis(Octadecanoyloxy)propyl]oxy}(Hydroxy)phosphoryl]-L-Serine • Phosphatidylserine [INCI] • Phosphatidylserine(18:0/18:0) • Phosphatidylserine(36:0) • Phosphotidylserine • PS(18:0/18:0) • PSer(18:0/18:0) • PSer(36:0) • UNII-394XK0IH40
CAS Number
IUPAC Name: (2S)-2-amino-3-[[(2R)-2,3-di(octadecanoyloxy)propoxy]-hydroxyphosphoryl]oxypropanoic acid
PubChem CID: 9547096

Summary

Species	No. Entries	MAX(Avg/Med Lifespan Change %)	MEAN(Avg/Med Lifespan Change %)	MAX(Max Lifespan Change %)	MEAN(Max Lifespan Change %)

Results

Compound/Formulation	Species	Sex	Strain	Dosage	Avg/Med Lifespan Change (%)	Avg/Med Lifespan Significance	Max Lifespan Change (%)	Reference

Lifespan Charts for Phosphatidylserine

Average/Median Lifespan
Max Lifespan
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References

Kim, BK and Park, SK (2020) Phosphatidylserine modulates response to oxidative stress through hormesis and increases lifespan via DAF-16 in Caenorhabditis elegans. Biogerontology 21(2)231-244 PubMed

DGIdb Human Drug-Gene Interactions for Phosphatidylserine

Interaction Types	Gene Symbol	Common Name	HGNC Id	DGIdb Sources	References

Stitch DB Human Drug-Protein Interactions for Phosphatidylserine

Up to 20 direct protein and drug interactions are displayed, having a medium confidence score (0.450) or above. Second order interactions are tabulated below.

Ensembl Id	StringDB Id