DrugAge entry for Phenylbutazone

Name: Phenylbutazone
Synonyms: 4-Butyl-1,2-diphenylpyrazolidine-3,5-dione • 50-33-9 • Alkabutazona • Azolid • Butacote • Butadion • Butapirazol • Butapirazole • Butapyrazole • Butazolidin • Butazolidine • Bute • Chembutazone • Diphenylbutazone • Fenibutazona • Fenilbutazona • Fenylbutazon • Intrabutazone • Mephabutazon • Phenylbutazonum
CAS Number: 50-33-9
IUPAC Name: 4-butyl-1,2-diphenylpyrazolidine-3,5-dione
PubChem CID: 4781

Summary

Species	No. Entries	MAX(Avg/Med Lifespan Change %)	MEAN(Avg/Med Lifespan Change %)	MAX(Max Lifespan Change %)	MEAN(Max Lifespan Change %)

Results

Compound/Formulation	Species	Sex	Strain	Dosage	Avg/Med Lifespan Change (%)	Avg/Med Lifespan Significance	Max Lifespan Change (%)	Reference

Lifespan Charts for Phenylbutazone

Average/Median Lifespan
Max Lifespan
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References

Hochschild, R. (1971) Effect of membrane stabilizing drugs on mortality in Drosophila melanogaster. Exp Gerontol 6(2)133-151 PubMed

DGIdb Human Drug-Gene Interactions for Phenylbutazone

Interaction Types	Gene Symbol	Common Name	HGNC Id	DGIdb Sources	References

Stitch DB Human Drug-Protein Interactions for Phenylbutazone

Up to 20 direct protein and drug interactions are displayed, having a medium confidence score (0.450) or above. Second order interactions are tabulated below.

Ensembl Id	StringDB Id