DrugAge entry for Perphenazine

Name: Perphenazine
Synonyms: 2-(4-(3-(2-Chloro-10H-phenothiazin-10-yl)propyl)piperazin-1-yl)ethanol • 58-39-9 • C21H26ClN3OS • Chlorperphenazine • Chlorpiprazine • Decentan • Emesinal • Etaperazin • Etaperazine • Ethaperazine • F-mon • Fentazin • Perfenazina • Perfenazine • Perphenan • Perphenazin • perphenazine • Perphenazinum • Sch 3940 • Thilatazin • Tranquisan • Trifaron • Trilafon • Trilifan • Triphenot
CAS Number: 58-39-9
IUPAC Name: 2-[4-[3-(2-chlorophenothiazin-10-yl)propyl]piperazin-1-yl]ethanol
PubChem CID: 4748

Summary

Species	No. Entries	MAX(Avg/Med Lifespan Change %)	MEAN(Avg/Med Lifespan Change %)	MAX(Max Lifespan Change %)	MEAN(Max Lifespan Change %)

Results

Compound/Formulation	Species	Sex	Strain	Dosage	Avg/Med Lifespan Change (%)	Avg/Med Lifespan Significance	Max Lifespan Change (%)	Reference

Lifespan Charts for Perphenazine

Average/Median Lifespan
Max Lifespan
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References

Lombard, DB et al. (2020) High-throughput small molecule screening reveals Nrf2-dependent and -independent pathways of cellular stress resistance. Sci Adv 6(40) PubMed

DGIdb Human Drug-Gene Interactions for Perphenazine

Interaction Types	Gene Symbol	Common Name	HGNC Id	DGIdb Sources	References

Stitch DB Human Drug-Protein Interactions for Perphenazine

Up to 20 direct protein and drug interactions are displayed, having a medium confidence score (0.450) or above. Second order interactions are tabulated below.

Ensembl Id	StringDB Id