DrugAge entry for PNU-74654

Name: PNU-74654
Synonyms: (E)-N'-((5-methylfuran-2-yl)methylene)-2-phenoxybenzohydrazide • 113906-27-7 • AC-33054 • AKOS024457670 • B7422 • BDBM50436058 • Benzoic acid, 2-phenoxy-, 2-[(5-methyl-2-furanyl)methylene]hydrazide • BS-14339 • CCG-208115 • CHEMBL254381 • CS-6211 • EX-A2520 • HMS3413P04 • HMS3677P04 • HY-101130 • MFCD12912438 • N-[(E)-(5-Methylfuran-2-yl)methylideneamino]-2-phenoxybenzamide • NSC-755984 • NSC755984 • PNU 74654 • PNU-74654 • PNU-74654, >=98% (HPLC), solid • PNU74654 • S8429 • SCHEMBL3514174
CAS Number
IUPAC Name: N-[(E)-(5-methylfuran-2-yl)methylideneamino]-2-phenoxybenzamide
PubChem CID: 9836739

Summary

Species	No. Entries	MAX(Avg/Med Lifespan Change %)	MEAN(Avg/Med Lifespan Change %)	MAX(Max Lifespan Change %)	MEAN(Max Lifespan Change %)

Results

Compound/Formulation	Species	Sex	Strain	Dosage	Avg/Med Lifespan Change (%)	Avg/Med Lifespan Significance	Max Lifespan Change (%)	Reference

Lifespan Charts for PNU-74654

Average/Median Lifespan
Max Lifespan
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References

Lombard, DB et al. (2020) High-throughput small molecule screening reveals Nrf2-dependent and -independent pathways of cellular stress resistance. Sci Adv 6(40) PubMed

DGIdb Human Drug-Gene Interactions for PNU-74654

Interaction Types	Gene Symbol	Common Name	HGNC Id	DGIdb Sources	References

Stitch DB Human Drug-Protein Interactions for PNU-74654

Up to 20 direct protein and drug interactions are displayed, having a medium confidence score (0.450) or above. Second order interactions are tabulated below.

Ensembl Id	StringDB Id